“A CLINICAL STUDY TO EVALUATE THE EFFECTIVENESS OF AN AYURVEDIC INDIGINOUS COMPOUND IN CASES OF URDHWAGA AMLAPITTA w.s.r GERD”

Abstract

Aim: To evaluate the efficacy of an ayurvedic indigenous compound in cases of urdhwaga amla-pitta. Introduction: Amla-pitta is one of the common clinical problems of our day to practice and it is increasing rapidly due to changes in our life style & high level of mental stress. Settings and Design: For the present clinical study 50 patients were selected. The patients having Indigestion, Nausea, Retrosternal burning, Anorexia, Acid eructation, Relief by sweet & cold food were selected for present clinical study. Materials and method: All patients were divided in two groups -Group-A- 25 patients were kept onyastimadhu ghana satva 800mg and amalki kwath bhavit sankh bhasma 200 mg in form of 2 capsule of 500 mg BD/ day after meal for a period of 6 weeks.Group-B-25 patients were kept on placebo (1000 mg wheat flour)2 capsule of 500 mg BD/ day after meal for a period of 6 weeks with aahar & vihar (Life style modification).Type of study: Phase 2 Rationale Randomized control trial. Statistical analysis used: p value, paired‘t’ test, unpaired‘t’ test, χ2 etc. Results: The trial drugs show significant results in terms of cure & improvement in clinical parameters and no any side effect has been observed. Conclusion: In cured patients response of treatment in group A is more than group B however group B has good response in improved patients so it’s suggested that for urdhwaga amlapitta both drug treatment and life style modification is of great importance.

Key words: Yastimadhu, Amalki, Sankh Bhasma, Urdhwaga amlapitta