PHYTOCHEMICAL SCREENING AND ANTI-ARTHRITIC ACTIVITY OF METHANOLIC LEAVES EXTRACT OF ANDROGRAPHIS PANICULATA

Abstract

Andrographis paniculata leaves are a herb widely distributed in tropical areas of Asia and Australia. This herb is cultivated across the globe firmly as a vegetable source. Andrographis paniculata are used intraditional medicinal system as anti-inflammatory agent, liver tonic, cardiotonic, skin infection, antiulcer etc. Number of phytochemical and pharmacological work has been carried out on deferent partsof Andrographis paniculata, prime objective of the study to find out Anti-Arthritic activity of methanolic extract of Andrographis paniculata. Methanolic extracts are rich of Alkaloids, glycosides, Diterpenes, saponins, flavonoids and  phenol are also responsible for inflammatory induced Antiarthritic activity, presence of secondary metabolite phyto-constituents encourages the current work. Results of the current study shows that Andrographis paniculata having significant anti-arthritic activity.

Keywords: Anti-arthritic, Carrageenan, Freund’s adjuvant, Methanolic extract,  Andrographis paniculata.